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Role of dose order in the development of tolerance to effects of cocaine on schedule-controlled behavior in pigeons

โœ Scribed by Michelle L. Miller; Marc N. Branch

Book ID
105880051
Publisher
Springer
Year
2002
Tongue
English
Weight
270 KB
Volume
163
Category
Article
ISSN
0033-3158

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โœ Jonathan L. Katz ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer ๐ŸŒ English โš– 366 KB

Schedule-controlled responding was maintained under a multiple fixed-interval, fixed-ratio schedule in pigeons. Dose-related decreases in response rates were produced by clonidine (0.00a-0.1mg/kg) and morphine (0.3-5.6 mg/kg). Chronic administration of morphine produced (1) tolerance to effects of m