Altering cytochrome P4501A activity affe
โ
Stephanie A. Hawkins; Sonya M. Billiard; Samir P. Tabash; R. Stephen Brown; Pete
๐
Article
๐
2002
๐
John Wiley and Sons
๐
English
โ 116 KB
## Abstract The polycyclic aromatic hydrocarbons (PAHs) phenanthrene and retene (7โisopropylโ1โmethyl phenanthrene) are lethal to rainbow trout __(Oncorhynchus mykiss)__ larvae during chronic exposures. Phenanthrene is a lowโtoxicity, nonโcytochrome P4501A (CYP1A)โinducing compound that accumulates