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Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response

✍ Scribed by Martin D. Lewis; Ben J. Roberts

Book ID: 116177300
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 649 KB
Volume: 436
Category: Article
ISSN: 0003-9861
DOI: 10.1016/j.abb.2005.02.010

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## Abstract BAG‐1 (Bcl‐2 associated athanogene‐1) is a multifunctional protein, linking cell proliferation, cell death, protein folding, and cell stress. In vivo, BAG‐1 is expressed in growth plate and articular cartilage, and the expression of BAG‐1 is decreased with aging. Chondrocytes respond to