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Role of clinical criteria in the diagnosis of hereditary non-polyposis colorectal cancer (HNPCC): Results of a multivariate analysis

✍ Scribed by Antonio Percesepe; Marcello Anti; Giancarlo Marra; Luca Roncucci; Marco Pahor; Claudio Ccco; Franco Armelao; Giovanni Gasbarrini; Maurizio Ponz De Leon


Publisher
John Wiley and Sons
Year
1994
Tongue
French
Weight
486 KB
Volume
58
Category
Article
ISSN
0020-7136

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## Abstract Clinical criteria, microsatellite analysis (MSA) and immunohistochemistry (IHC) are important diagnostic tools for identification of hereditary nonpolyposis colorectal cancer (HNPCC) patients who are likely to carry pathogenic germline mutations in mismatch repair genes. Based on MSA an