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Role of CHEK2*1100delC in unselected series of non-BRCA1/2 male breast cancers

✍ Scribed by Susan Neuhausen; Alison Dunning; Linda Steele; Kazuko Yakumo; Michael Hoffman; Csilla Szabo; Louise Tee; Caroline Baines; Paul Pharoah; David Goldgar; Doug Easton

Publisher: John Wiley and Sons
Year: 2003
Tongue: French
Weight: 44 KB
Volume: 108
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.11385

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## Abstract Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes __BRCA1__ and __BRCA2__, found in about 25% of high‐risk families, as well as few other low penetrance genes such as __ATM__ and __CHEK2__. Approximately two‐thirds of the multiple cases fa