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Mutational analyses of BRCA1 and BRCA2 in Ashkenazi and non-Ashkenazi Jewish women with familial breast and ovarian cancer

✍ Scribed by Ronit Shiri-Sverdlov; Peter Oefner; Limor Green; Ruth Gershoni Baruch; Teresa Wagner; Anna Kruglikova; Samario Haitchick; Robert M.W. Hofstra; Moshe Z. Papa; Inge Mulder; Shulamit Rizel; Revital Bruchim Bar Sade; Efrat Dagan; Ziad Abdeen; Boleslaw Goldman; Eitan Friedman


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
342 KB
Volume
16
Category
Article
ISSN
1059-7794

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BRCA1-related breast cancer in Austrian
✍ Teresa M. U. Wagner; Regine A. MΓΆslinger; Daniela Muhr; Gudrun Langbauer; Kora H πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 76 KB πŸ‘ 2 views

We identified 17 BRCA1 mutations in 86 Austrian breast and ovarian cancer families (20%) that were screened for mutations by denaturing high-performance liquid chromatography (DHPLC) and the protein truncation test (PTT). Eleven distinct mutations were detected, 4 of them (962del4, 2795del4, 3135del