We identified 17 BRCA1 mutations in 86 Austrian breast and ovarian cancer families (20%) that were screened for mutations by denaturing high-performance liquid chromatography (DHPLC) and the protein truncation test (PTT). Eleven distinct mutations were detected, 4 of them (962del4, 2795del4, 3135del
β¦ LIBER β¦
Mutational analyses of BRCA1 and BRCA2 in Ashkenazi and non-Ashkenazi Jewish women with familial breast and ovarian cancer
β Scribed by Ronit Shiri-Sverdlov; Peter Oefner; Limor Green; Ruth Gershoni Baruch; Teresa Wagner; Anna Kruglikova; Samario Haitchick; Robert M.W. Hofstra; Moshe Z. Papa; Inge Mulder; Shulamit Rizel; Revital Bruchim Bar Sade; Efrat Dagan; Ziad Abdeen; Boleslaw Goldman; Eitan Friedman
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 342 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1059-7794
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