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Role of CD46 in the class II restricted presentation of measles virus antigens

✍ Scribed by B. Horvat; P. Rivailler; M.C. Trescol-Biémont; C. Gimenez; C. Rabourdin-Combe

Book ID
108409046
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
368 KB
Volume
56
Category
Article
ISSN
0165-2478

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Efficient MHC Class II-restricted presentation of measles virus to T cells relies on its targeting to its cellular receptor human CD46 and involves an endosomal pathway
✍ D. Gerlier; M.-C. Trescol-Biémont; G. Varior-Krishnan; D. Naniche; I. Fugier-Viv 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 297 KB

## ABSTRACT The role of the measles virus (MV) receptor, human CD46, in the uptake of MV and antigen presentation by Major Histocompatibility Complex (MHC) class II molecules was investigated. Expression of CD46 in murine B cells resulted in cells highly efficient in capturing UV‐inactivated MV par