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Role of CD18-dependent and CD18-independent mechanisms in the increased leukocyte adhesiveness and in the variations of circulating white blood cell populations induced by anti-CD3 monoclonal antibodies

✍ Scribed by Paul Kinnaert; Olivier Pradier; Bernadette Bournonville; Claude Habrant; Michel Goldman; Nancy Geertruyden


Publisher
Springer
Year
1996
Tongue
English
Weight
579 KB
Volume
9
Category
Article
ISSN
0934-0874

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## Abstract The cure of human Hodgkin's tumors heterotransplanted into SCID mice can be achieved by two bispecific monoclonal antibodies (Bi‐mAb) directed against the tumor‐associated CD30 antigen and CD3 and CD28, respectively, and normal peripheral human blood T cells. We investigated the role of