Role of calcium in the release of EC 3.4.24.15 and EC 3.4.24.16 from endothelial cells
โ Scribed by M. Ursula Norman; A. Ian Smith; Rebecca A. Lew
- Book ID
- 110271969
- Publisher
- Springer Netherlands
- Year
- 1999
- Tongue
- English
- Weight
- 45 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1573-3149
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## Abstract Endopeptidase 24.15 (EP24.15) and 24.16 (EP24.16) are closely related metalloendopeptidases implicated in the metabolism of several neuropeptides and widely expressed in mammalian brain. To gain insight into the functional role of these two enzymes in the central nervous system, we exam
## Abstract Neuropeptide processing metalloenzymes, such as angiotensin converting enzyme, neprilysin, endothelin converting enzyme, neurolysin, and EC3.4.24.15 (EP24.15), are central to the formation and degradation of bioactive peptides. We present EP24.15 as a paradigm for novel functions ascrib