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Role of Bcl-2 family proteins (Bax, Bcl-2 and Bcl-X) on cellular susceptibility to radiation in pancreatic cancer cells

โœ Scribed by J.-U Lee; R Hosotani; M Wada; R Doi; T Kosiba; K Fujimoto; Y Miyamoto; S Tsuji; S Nakajima; Y Nishimura; M Imamura


Book ID
117666792
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
296 KB
Volume
35
Category
Article
ISSN
0959-8049

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Down-regulation of apoptosis-related bcl
โœ Besim Ogretmen; Ahmad R. Safa ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 797 KB

Recent studies have shown that high levels of the apoptosisrelated proteins bcl-2 and bcl-x, increase, while over-expression of bcl-x, or bax decreases, resistance to drugs that induce apoptosis in some human cancer cells. In the present report, we investigated whether expression of these apoptosis-