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Role of Bcl-2 family of proteins in mediating apoptotic death of PC12 cells exposed to oxygen and glucose deprivation

✍ Scribed by David Koubi; Hao Jiang; Lijie Zhang; Wenxue Tang; Jarret Kuo; Alba I. Rodriguez; Tangella Jackson Hunter; Michael D. Seidman; George B. Corcoran; Robert A. Levine

Book ID
116764569
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
326 KB
Volume
46
Category
Article
ISSN
0197-0186

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## Abstract In the present study, we examined how the cell survival signaling via cyclic AMP‐responsive element binding protein (CREB) and Akt, and the cell death signaling via cystein proteases, calpain and caspase‐3, are involved in oxygen‐glucose deprivation (OGD) followed by reoxygenation (OGD/