Role of bacteria and HLA-B27 in the pathogenesis of reactive arthritis
β Scribed by Yu, David; Kuipers, Jens G
- Book ID
- 123120077
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 245 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0889-857X
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Population and peptide specificity analyses and studies in transgenic rodents support a role of HLA-B27 as an antigen-presenting molecule in spondyloarthropathy. The interplay between HLA-B27 and arthritogenic bacteria on infected cells suggests that HLA-B27 might also influence disease by other mec
## Objective: To determine whether hla-b27 positive patients with ankylosing spondylitis (as) and reactive arthritis (rea) share additional hla factors that confer disease susceptibility. ## Methods: Hla class i antigens were typed serologically, and class ii antigens molecularly, in samples take