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Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

✍ Scribed by Kanzawa, T; Germano, I M; Komata, T; Ito, H; Kondo, Y; Kondo, S

Book ID
110016680
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
387 KB
Volume
11
Category
Article
ISSN
1350-9047

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## Abstract Malignant gliomas are common primary tumors of the central nervous system. The prognosis of patients with malignant glioma is poor in spite of current intensive therapy and thus novel therapeutic modalities are necessary. Imatinib mesylate, a tyrosine kinase inhibitor, is effective in t