𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells

✍ Scribed by Shigeo Ohba; Yuichi Hirose; Takeshi Kawase; Hirotoshi Sano


Publisher
Springer US
Year
2009
Tongue
English
Weight
384 KB
Volume
95
Category
Article
ISSN
0167-594X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Inhibition of autophagy at a late stage
✍ Takashi Shingu; Keishi Fujiwara; Oliver BΓΆgler; Yasuhiko Akiyama; Kouzo Moritake πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 800 KB

## Abstract Malignant gliomas are common primary tumors of the central nervous system. The prognosis of patients with malignant glioma is poor in spite of current intensive therapy and thus novel therapeutic modalities are necessary. Imatinib mesylate, a tyrosine kinase inhibitor, is effective in t

Cardiotoxin III induces c-jun N-terminal
✍ Ching-Ming Chien; Sheng-Huei Yang; Chun-Chieh Yang; Long-Sen Chang; Shinne-Ren L πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 233 KB πŸ‘ 1 views

## Abstract Cardiotoxin III (CTX III), a basic polypeptide with 60 amino acid residues isolated from __Naja naja atra__ venom, has been reported to have anticancer activity. The molecular effects of CTX III on HL‐60 cells were dissected in the present study. We found that the antiproliferative acti

Jun N-terminal kinase pathway enhances s
✍ Qing Wang; Xuening Wang; George P. Studzinski πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 617 KB

## Abstract Recent studies revealed that the MEK/ERK module of the mitogen‐activated protein kinase (MAPK) signaling cascades is up‐regulated in the early stages of 1Ξ±,25‐dihydroxyvitamin D~3~ (1,25D~3~)‐induced monocytic differentiation of human leukemia cells HL60. In the present study, we invest

2-deoxyglucose inhibits chemotheapeutic
✍ Naomi Haga; Mikihiko Naito; Hiroyuki Seimiya; Akihiro Tomida; Jian Dong; Takashi πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 119 KB πŸ‘ 2 views

Human monocytic leukemia U937 cells undergo apoptosis when treated with antitumor drugs, such as etoposide, camptothecin and mitomycin C. The molecular mechanism of the drug-induced apoptosis is not well understood. In this study, we found that 2-deoxyglucose (2DG), an analog of D-glucose and an ind

Calphostin C induces AP1 synthesis and A
✍ Mengkun Zhang; Caroline Miller; Yulan He; Johanne Martel-Pelletier; Jean-Pierre πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 213 KB πŸ‘ 2 views

Activator protein-1 (AP1) regulates the promoter activity of a large number of genes associated with developmental, proliferative, inflammatory, and homeostatic processes in human connective tissue cells. Some of these genes (e.g., cyclooxygenase-2) are regulated by the protein kinase C (PKC) inhibi