Role of ATP in Trauma-Associated Cytokine Release and Apoptosis by P2X7 Ion Channel Stimulation

ATP binding cassette transporter ABC1 is

ATP binding cassette transporter ABC1 is required for the release of interleukin-1β by P2X7-stimulated and lipopolysaccharide-primed mouse Schwann cells

✍ Vincent Marty; Chantal Médina; Chantal Combe; Patricia Parnet; Thierry Amédée 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB 👁 1 views

Schwann cells are best known as myelinating glial cells of the peripheral nervous system, but they also participate actively in the sphere of immunity by producing pro-inflammatory cytokines, such as interleukin-1␤ (IL-1␤). In a previous study, we demonstrated that posttranslational processing of IL