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Role of Astrocytes in Depolarization-Coupled Release of Glutamate in Cerebellar Cultures

โœ Scribed by Lasse K. Bak; Helle S. Waagepetersen; Arne Schousboe

Book ID
111602193
Publisher
Springer
Year
2004
Tongue
English
Weight
115 KB
Volume
29
Category
Article
ISSN
0364-3190

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Novel metabotropic glutamate receptor ne
Novel metabotropic glutamate receptor negatively coupled to adenylyl cyclase in cultured rat cerebellar astrocytes
โœ Srinivasan Kanumilli; Nick J. Toms; Peter J. Roberts ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 183 KB

## Abstract Several excitatory amino acid ligands were found potently to inhibit forskolinโ€stimulated cAMP accumulation in rat cultured cerebellar astrocytes: Lโ€cysteine sulfinic acid (Lโ€CSA) = Lโ€aspartate > Lโ€glutamate โ‰ฅ the glutamate uptake inhibitor, Lโ€PDC. This property did not reflect activati