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Role of ascorbic acid in transferrin-independent reduction and uptake of iron by U-937 cells

✍ Scribed by James M May; Zhi-chao Qu; Shalu Mendiratta


Book ID
113994385
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
216 KB
Volume
57
Category
Article
ISSN
0006-2952

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HFE-related hereditary hemochromatosis results in hepatic iron overload. Hepatocytes acquire transferrin-bound iron via transferrin receptor (Tfr) 1 and Tfr1-independent pathways (possibly Tfr2-mediated). In this study, the role of Hfe in the regulation of hepatic transferrin-bound iron uptake by th