Role of aquaporins in cell migration and edema formation in human brain tumors
β Scribed by Beatrice Nico; Domenico Ribatti
- Book ID
- 113956125
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 596 KB
- Volume
- 317
- Category
- Article
- ISSN
- 0014-4827
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π SIMILAR VOLUMES
Neurotrauma is the leading cause of death and disability in young adults, and the incidence in older patients is increasing. Neurotrauma is also a field in medicine with one of the highest unmet needs. Concentrated, focused and multidisciplinary efforts are required to combat this important disease.
## Abstract Aquaporinβ4 (AQP4), a water channel protein, is abundantly expressed in astrocytes and plays a key role in the development of brain edema. However, it is not clear whether AQP4 contributes to astrocytic swelling in hypoxiaβischemia (HI). To investigate the roles of AQP4 in astrocytic sw