Effect of hyperoxia treatment on aquaporin 4 changes and edema formation in the contralateral brain after neonatal hypoxia/ischemia

The roles of aquaporin-4 in brain edema

The roles of aquaporin-4 in brain edema following neonatal hypoxia ischemia and reoxygenation in a cultured rat astrocyte model

✍ Xuemei Fu; Qiuping Li; Zhichun Feng; Dezhi Mu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 350 KB 👁 1 views

## Abstract Aquaporin‐4 (AQP4), a water channel protein, is abundantly expressed in astrocytes and plays a key role in the development of brain edema. However, it is not clear whether AQP4 contributes to astrocytic swelling in hypoxia–ischemia (HI). To investigate the roles of AQP4 in astrocytic sw