Role of antibodies and effect of BCG vaccination in experimental candidiasis in mice
โ Scribed by Pradip K. Maiti; Ashok Kumar; Ramesh Kumar; L. N. Mohapatra
- Publisher
- Springer Netherlands
- Year
- 1985
- Tongue
- English
- Weight
- 500 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0301-486X
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Objective. To investigate the pathogenetic role of antineutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis (WG). Methods. BALBlc mice were immunized with human IgG ANCA from a patient with WG. Control mice were immunized with normal human IgG. Levels of mouse ANCA and other autoant
Two BCG vaccine preparations were prepared following different production methods. Immuno-BCG Pasteur F was produced by surface culture on Sauton medium; BCG-R1V was a homogenous stirred deep culture. The antitumor effects of the two BCG vaccines were investigated on the Lewis lung carcinoma (3LL)
Rabbits were employed as experimental models to evaluate a solid-phase radioimmunoassay (RIA) method for the diagnosis of systemic candidiasis. Ten rabbits were inoculated subcutaneously to mimic superficial candidiasis and were found to produce no antibodies to Candida as determined by both immunod