Role of analytical ultracentrifugation in assessing the aggregation of protein biopharmaceuticals
โ Scribed by Steven A. Berkowitz
- Book ID
- 118728875
- Publisher
- American Association of Pharmaceutical Scientists
- Year
- 2006
- Tongue
- English
- Weight
- 779 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1550-7416
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A method is described whereby sedimentation velocity is combined with equilibrium dialysis to determine the net charge (valence) of a protein by using chromate as an indicator ion for assessing the extent of the Donnan redistribution of small ions. The procedure has been used in experiments on bovin
The compositional buoyant densities, p8, of human y-immunoglobulin, bovine serum mercaptalbumin, and egg albumin have been measured in CsCl solutions in the analytical ultracentrifuge as a function of pressure. Standard pressure coefficients, $0, and standard partial specific volumes of the solvated