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Role of altered osteoblastic expression of Dkk-1 in the pathogenesis of osteoarthritis and osteoporosis

✍ Scribed by A. Corrado; A. Neve; A. Macchiarola; A.M. Gaudio; A. Marucci; F.P. Cantatore


Book ID
116324300
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
59 KB
Volume
48
Category
Article
ISSN
8756-3282

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The role of Dkk1 in bone mass regulation
✍ Joseph S. Butler; David W. Murray; Conor J. Hurson; Julie O'Brien; Peter P. Dora πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 168 KB

## Abstract The Wnt/β‐catenin pathway is a major signaling cascade in bone biology, playing a key role in regulating bone development and remodeling, with aberrations in signaling resulting in disturbances in bone mass. The objectives of our study were to correlate serum Dkk1 expression with bone m