Protein kinase C family functions in B-c
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Beichu Guo; Thomas T Su; David J Rawlings
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Article
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2004
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Elsevier Science
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English
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Members of the protein kinase C (PKC) family play important but distinct roles in B-cell activation, as demonstrated by emerging genetic and biochemical studies. PKCb is indispensable for B-cell antigen receptor (BCR)-induced NF-kB activation and B-cell survival. Recent evidence indicates that PKCb