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Role for protein kinase C activation in IgA B cell terminal differentiation

โœ Scribed by Yue Sheng Li; Marie-Therese Dearden-Badet; Jean-Pierre Revillard


Book ID
112937240
Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
258 KB
Volume
10
Category
Article
ISSN
0257-277X

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Protein kinase C family functions in B-c
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Members of the protein kinase C (PKC) family play important but distinct roles in B-cell activation, as demonstrated by emerging genetic and biochemical studies. PKCb is indispensable for B-cell antigen receptor (BCR)-induced NF-kB activation and B-cell survival. Recent evidence indicates that PKCb