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Role for NK-cell-associated Fas ligand in cell-mediated cytotoxicity and apoptosis

✍ Scribed by C.M. Eischen; P.J. Leibson

Book ID
117614815
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
512 KB
Volume
148
Category
Article
ISSN
0923-2494

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The relationship between Fas-mediated apoptosis and Type 1 diabetes is currently under investigation. Fas/Fas ligand interaction could be involved both in the insulitis process and in beta-cell death. Nevertheless, different mechanisms appear to be involved in human Type 1 diabetes and in NOD mice.