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RNA Recognition and Cleavage by the SARS Coronavirus Endoribonuclease

✍ Scribed by Kanchan Bhardwaj; Jingchuan Sun; Andreas Holzenburg; Linda A. Guarino; C. Cheng Kao

Book ID
116663120
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
877 KB
Volume
361
Category
Article
ISSN
0022-2836

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The different extent of the target RNA cleavage at t 99.9% by RNase H in the AON-RNA duplexes, at the RNA saturation condition by antisense oligo, is due to different recognition and catalytic properties of RNase H toward the hybrids owing to different substituents at the 3%-end of the AONs, not owi