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RNA interference targeting Fas protects mice from fulminant hepatitis

โœ Scribed by Song, Erwei; Lee, Sang-Kyung; Wang, Jie; Ince, Nedim; Ouyang, Nengtai; Min, Jun; Chen, Jisheng; Shankar, Premlata; Lieberman, Judy


Book ID
109933234
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
547 KB
Volume
9
Category
Article
ISSN
1078-8956

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๐Ÿ“œ SIMILAR VOLUMES


RNA interference targeting Fas protects
โœ Song, Erwei; Lee, Sang-Kyung; Wang, Jie; Ince, Nedim; Ouyang, Nengtai; Min, Jun; ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 547 KB

RNA interference (RNAi) is a powerful tool to silence gene expression post-transcriptionally 1 . However, its potential to treat or prevent disease remains unproven. Fas-mediated apoptosis is implicated in a broad spectrum of liver diseases, where inhibiting hepatocyte death is life-saving 2 . We in