In 1989, three laboratories (in Canada, France and Germany) independently and simultaneously reported the discovery of C-to-U RNA editing in plant mitochondria (1-3). To mark the 20th anniversary of this finding, the leaders of the three research teams have written personal essays describing the eve
RNA editing in the mitochondria of a conifer
β Scribed by Jeffrey C. Glaubitz; John E. Carlson
- Publisher
- Springer-Verlag
- Year
- 1992
- Tongue
- English
- Weight
- 295 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0172-8083
No coin nor oath required. For personal study only.
β¦ Synopsis
A 712-base portion of the mitochondrial gene coxI and the corresponding portion of the coxI transcript were amplified by PCR and by RT-PCR, respectively, from the gymnosperm western red cedar. Sequence comparison of amplified coxI DNA and mRNA revealed 26 C-to-U differences that are best explained by RNA editing of the type known to occur in angiosperms. This finding suggests that mitochondrial RNA-editing of the C-to-U type arose before the divergence of gymnosperms and angiosperms and can be considered a feature common to all higher plants.
π SIMILAR VOLUMES
## Abstract A single C/T difference between gene and cDNA within the 5β²βuntranslated region of the wheat mtDNAβencoded __cox2__ (cytochrome oxidase subunit 2) sequence catalyzed the discovery of CβtoβU RNA editing in plant mitochondria by a group at Dalhousie University in Halifax, Nova Scotia [Cov