𝔖 Bobbio Scriptorium
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Risks and Benefits of Phase 1 Oncology Trials, Revisited

✍ Scribed by Razelle Kurzrock; Robert S Benjamin

Book ID
114332986
Publisher
Medknow Publications
Year
2008
Weight
43 KB
Volume
5
Category
Article
ISSN
0976-0016

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Risks and benefits associated with novel
Risks and benefits associated with novel phase 1 oncology trial designs
✍ Shlomo A. Koyfman; Manish Agrawal; Elizabeth Garrett-Mayer; Benjamin Krohmal; El πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 210 KB

## Abstract ## BACKGROUND. Although aggressive dose escalation strategies were designed to improve the risk‐benefit profile of phase 1 oncology trials, they have not been adequately studied. The prevalence of several novel trial designs and their association with a variety of clinical endpoints wa