𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Risk prediction with linked markers: Pedigree analysis

✍ Scribed by Rogatko, André ;Rebbeck, Timothy ;Zacks, Shelemyahu

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
783 KB
Volume
59
Category
Article
ISSN
0148-7299

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Risk prediction with linked markers: The
Risk prediction with linked markers: Theory
✍ Rogatko, André 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 877 KB

A Bayesian method to predict disease recurrence risks based on distance information between loci and allowing for uncertain gene location is presented. The methodology allows derivation of the posterior distribution of recurrence risks, from which point estimates and associated precision measures ca

Utilizing automated methods to improve e
Utilizing automated methods to improve estimates of recurrence risk with linked genetic markers
✍ Price, R. Arlen ;Kidd, Kenneth K. ;Opitz, John M. 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 310 KB 👁 1 views

Information on linked markers can greatly improve estimates of recurrence risk for genetic disorders. However, when linkage is incomplete, utilizing the information in genetic counseling requires complex, repetitive calculations to estimate correct risks whenever the parental linkage phase is not pr

X-LRT: a likelihood approach to estimate
X-LRT: a likelihood approach to estimate genetic risks and test association with X-linked markers using a case-parents design
✍ Li Zhang; Eden R. Martin; Ren-Hua Chung; Yi-Ju Li; Richard W. Morris 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB 👁 1 views

## Abstract Recently, there has been interest in family‐based tests of association to identify X‐chromosome genes. However, none of the approaches allow for estimation of genetic risks. We propose a likelihood approach to estimate disease‐related marker relative risks and test genotype association