Risk of extramedullary relapse following allogeneic bone marrow transplantation for acute myelogenous leukemia with leukemia cutis
โ Scribed by Michel, G; Boulad, F; Small, T N; Black, P; Heller, G; Castro-Malaspina, H; Childs, B H; Gillio, A P; Papadopoulos, E B; Young, J W
- Book ID
- 110010187
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 146 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0007-1188
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The curative effect of allogeneic bone marrow transplantation (BMT) for acute and chronic leukemia is attributed to the intensive conditioning chemotherapy with or without radiotherapy, as well as an immune-mediated graft versus leukemia (GVL) effect. A different pattern of relapse has been observed
Allogeneic stem cell transplantation is considered to be a curative treatment modality in patients with chronic myelogenous leukemia. However patients are at risk for relapse years after transplantation. Currently we present two patients who relapsed 16 and 24 years after allogeneic bone marrow tran