A case of porphyria cutanea terda (PCT) occurring after bone marrow transplantation (BMT) is reported. A 43-year-oid male with chronic myelogenous leukemia received an human leukocyte antigen (HLA)-identical allogeneic transplantation with T-cell depleted marrow. Because of graft rejection, a second
Very late relapse of chronic myelogenous leukemia after allogeneic bone marrow transplantation
β Scribed by Arunabh Sekhri; Delong Liu; Muhammad Rasul; Nasir Ahmed; Tauseef Ahmed; Karen Seiter
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 99 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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β¦ Synopsis
Allogeneic stem cell transplantation is considered to be a curative treatment modality in patients with chronic myelogenous leukemia. However patients are at risk for relapse years after transplantation. Currently we present two patients who relapsed 16 and 24 years after allogeneic bone marrow transplantation, respectively. These patients emphasize the need for long term follow-up of such patients.
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The curative effect of allogeneic bone marrow transplantation (BMT) for acute and chronic leukemia is attributed to the intensive conditioning chemotherapy with or without radiotherapy, as well as an immune-mediated graft versus leukemia (GVL) effect. A different pattern of relapse has been observed