𝔖 Bobbio Scriptorium
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Risk factors of the cutaneous melanoma phenotype

✍ Scribed by Ernst G. Jung; Kurt Günthart; Roland F. G. Metzger; Elisabeth Bohnert

Publisher
Springer-Verlag
Year
1981
Tongue
English
Weight
236 KB
Volume
270
Category
Article
ISSN
0340-3696

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✦ Synopsis

Of 20 melanoma patients 85% show a prolonged erythema persistence after a marked test erythema of 8 MED with 300 nm _+ 10 nm (control group only 34 %).

This phenomenon does not correlate with the skin type and is useful in identifying high-risk patients prone to melanoma and light-induced skin cancer (92%).

The spontaneous and the UV-C-induced number of sister chromatid exchanges (SCE) per metaphase was significantly higher in peripheral leukocytes of melanoma patients than in normal controls. The attempt was made to establish a "risk-spectrum" of cutaneous melanoma phenotype.

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