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Risk factors for cutaneous malignant melanoma in a northern italian population

โœ Scribed by Mario Cristofolini; Laura Tasin; Giuseppe Zumiani; Silvia Franceschi; Renato Talamini; Francesco Piscioli; Carlo La Vecchia


Publisher
John Wiley and Sons
Year
1987
Tongue
French
Weight
509 KB
Volume
39
Category
Article
ISSN
0020-7136

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โœฆ Synopsis


The relationship between cutaneous malignant melanoma (CMM) and the colour of skin, hair and eyes, the extent of sun exposure and reaction to it, education, and the occurrence of skin neoplasms in patients and their families was evaluated in a case-control study of 103 cases of CMM and 205 control subjects hospitalized for acute conditions other than malignant or hormonal disease. A significantly higher risk was associated with fair skin as compared to dark/medium skin (RR = 4.0; 95% CI: 1.5-10.5) and positive family history for CMM (RR = 8.1; 95% CI: 1.0-200.9). CMM seemed to occur more frequently, but not significantly so, in individuals with brown or blond hair, higher education and clinically diagnosed dysplastic naevi. Outdoor occupation and heavy sun exposure in the last 20 years seemed to increase the risk of CMM in sun-exposed sites but to be negatively associated with CMM in normally unexposed sites.


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