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Risk factors for wound infection in head and neck cancer surgery: A prospective study

✍ Scribed by Nicolas Penel; Daniéle Lefebvre; Charles Fournier; Jèrome Sarini; Ahmed Kara; Jean-Louis Lefebvre

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
102 KB
Volume
23
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background

The goal of this prospective study is to determine risk factors for wound infections (WI) for patients with head and neck cancer who underwent surgical procedure with opening of upper aerodigestive tract mucosa.

Methods

One hundred sixty‐five consecutive surgical procedures were studied at Oscar Lambret Cancer Center within a 24‐month interval. Twenty‐five variables were recorded for each patient. Statistical evaluation used X^2^ test analysis (categorical data) and Mann–Whitney test (continuous variables).

Results

The overall rate of WI was 41.8%. Univariate analysis indicated that five variables were significantly related to the likelihood of WI: tumor stage (p = .044), previous chemotherapy (p = .008), duration of preoperative hospital stay (p = 022), permanent tracheostomy (p = .00008), and hypopharyngeal and laryngeal cancers (p = .008).

Conclusions

Despite antibiotic prophylaxis, WI occurrence is high. These data inform the head and neck surgeon, when a patient is at risk for WI and may help to design future prospective studies. © 2001 John Wiley & Sons, Inc. Head Neck 23: 447–455, 2001.

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