Ring opening of cyclohexene epoxide with trimethylsilyl cyanide
β Scribed by Gary O. Spessard; Allen R. Ritter; Dawn M. Johnson; Anne M. Montgomery
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 110 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Epoxides can be opened under neutral conditions with TMSN 3 and TMSCN in the presence of catalytic amounts of Lewis acid, affording the corresponding ring-opened compounds in high yields.
endo-2,3-Epoxy-1,7,7-trimethylbicyclo[2.2.1]heptane reacted with trimethylsilyl cyanide in the pre=e of zinc iodide to produce a complex mixture of products. The major product, anti-7-trimethylsiloxy-endo-2,3,3-trimethyl-exo-2-isocyanobicyclo[2.2.l]heptane was obtained in f2%yield. -In addition, ei
## Abstract The transformation proceeds under neutral conditions.