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Ring-Opening Cyclization of Alkylidenecyclopropyl Ketones with Amines. An Efficient Synthesis of 2,3,4-Trisubstituted Pyrroles

✍ Scribed by Lu, Lianghua; Chen, Guofei; Ma, Shengming


Book ID
120477903
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
93 KB
Volume
8
Category
Article
ISSN
1523-7060

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An efficient synthesis of 2,3,4-trisubst
✍ Dipti R. Patil; Sonali M. Salunkhe; Madhukar B. Deshmukh; Prashant V. Anbhule πŸ“‚ Article πŸ“… 2011 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 106 KB

## Abstract A series of 2,3,4‐trisubstituted quinoline derivatives have been synthesized by reactions between 2‐aminoaryl ketones and dialkyl acetylenedicarboxylate. The synthetic pathway allows for the direct construction of said quinoline derivatives in pyridine/ethanol at ambient temperature thr