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Ring-Opening Cyclization of Alkylidenecyclopropyl Ketones with Amines. An Efficient Synthesis of 2,3,4-Trisubstituted Pyrroles.

✍ Scribed by Lianghua Lu; Guofei Chen; Shengming Ma


Publisher
John Wiley and Sons
Year
2006
Weight
34 KB
Volume
37
Category
Article
ISSN
0931-7597

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An efficient synthesis of 2,3,4-trisubst
✍ Dipti R. Patil; Sonali M. Salunkhe; Madhukar B. Deshmukh; Prashant V. Anbhule 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 106 KB

## Abstract A series of 2,3,4‐trisubstituted quinoline derivatives have been synthesized by reactions between 2‐aminoaryl ketones and dialkyl acetylenedicarboxylate. The synthetic pathway allows for the direct construction of said quinoline derivatives in pyridine/ethanol at ambient temperature thr