Ring chromosomes in a retroperitoneal lipoma of childhood
β Scribed by Erika L. D. Mitchell; Anna Kelsey; Gordon Armstrong; Alan Dickson
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 331 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
We report here the presence of ring chromosomes in a retroperitoneal lipoma from a 12βyearβold male. Ring chromosomes are strongly associated with the pathological subtype βatypical lipomaβ in adults. In contrast, however, the tumour described here possesses no atypical features.
π SIMILAR VOLUMES
## Abstract Lipomas are frequently characterized by rearrangements resulting in the fusion of the __HMGA2__ gene (12q14.3) with a variety of partners. Chromosome band 9p22 rearrangements occur in about 1% of lipomas. We report here the molecular cytogenetic analysis of five cases of lipoma with a 9
## Background and procedure: During a 13-year period, 22 children were treated for rhabdomyosarcoma (rms). in 18 of these patients chromosome analysis was attempted on material from tumor biopsies, fine needle aspiration biopsies and/or bone marrow samples. ## Results: Clonal chromosome aberratio
During the last 54 years at the Children's Hospital 11 children (10 female, 1 male) had been treated for an extragonadal germ cell tumor arising in the retroperitoneum. There were eight teratomas (five mature, three immature), two endodermal sinus tumors and one tumor with a mixture of both componen