Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study
✍ Scribed by Abdelhamid Benazzouz; Thomas Boraud; Pierre Dubédat; Alain Boireau; Jean-Marie Stutzmann; Christian Gross
- Book ID
- 115890383
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 790 KB
- Volume
- 284
- Category
- Article
- ISSN
- 0014-2999
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Quantitative measures for the severity of MPTP-induced parkinsonism and response to antiparkinsonian interventions in monkeys have been lacking. We carried out an oral levodopa dose-response study in two rhesus monkeys whose left hemiparkinsonism was induced by intracarotid administration of MPTP. A
This report describes a method to assess, in vivo, the turnover of dopamine (DA) and describes its application to the evaluation of DA function in normal monkeys and monkeys with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced lesions of the DA nigro-striatal pathway. Using positron emis