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Neuropharmacological and neuropathological studies in the brain of MPTP-induced monkey parkinsonism

✍ Scribed by Kito, Shozo; Miyoshi, Rie; Nitta, Kosaku; Yamamura, Yasuhiro; Matsubayashi, Hiroaki

Book ID: 122585364
Publisher: Elsevier Science
Year: 1987
Weight: 72 KB
Volume: 5
Category: Article
ISSN: 0921-8696
DOI: 10.1016/0921-8696(87)90114-9

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This report describes a method to assess, in vivo, the turnover of dopamine (DA) and describes its application to the evaluation of DA function in normal monkeys and monkeys with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced lesions of the DA nigro-striatal pathway. Using positron emis