Ribozymes, genomics and therapeutics

✍ Scribed by John J Rossi

• Book ID: 104375790
• Publisher: Elsevier Science
• Year: 1999
• Tongue: English
• Weight: 506 KB
• Volume: 6
• Category: Article
• ISSN: 1074-5521
• DOI: 10.1016/s1074-5521(99)80001-5

✦ Synopsis

Genome-sequencing projects are proceeding at a rapid pace and determining the function of open reading frames is the next great challenge. Ribozymes with site-specific cleaving activity could aid greatly in this process. High-throughput screening methods to identify optimal target sites for ribozyme cleavage will provide tools for functional genomics as well as therapeutic reagents.