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Riboswitches as antibacterial drug targets

✍ Scribed by Blount, Kenneth F; Breaker, Ronald R

Book ID: 109909711
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 740 KB
Volume: 24
Category: Article
ISSN: 1087-0156
DOI: 10.1038/nbt1268

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## Abstract Current drug discovery efforts generally focus on a limited number of protein classes, typically including proteins with well‐defined catalytic active sites (e.g., kinases) or ligand binding sites (e.g., G protein‐coupled receptors). Nevertheless, many clinically important pathways are