The suppression of prion propagation usi
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Chongsuk Ryou; William B. Titlow; Charles E. Mays; Younsoo Bae; Sehun Kim
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Article
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2011
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Elsevier Science
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English
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Poly-L-lysine (PLL), a homopolymer of amino acid L-lysine (LL), has been frequently used for drug delivery. Here, we report that PLL is an effective agent to inhibit propagation of prions that cause fatal and incurable neurologic disorders in humans and animals, termed prion diseases. In our recent