Ribosomes from erythromycin-resistant mutants of Escherichia coli Q13
β Scribed by Otaka, Eiko; Teraoka, Hiroshi; Tamaki, Mikio; Tanaka, Kentaro; Osawa, Syozo
- Book ID
- 122786359
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- English
- Weight
- 759 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0022-2836
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π SIMILAR VOLUMES
We have studied the in vitro properties of ribosomes from several mutants resistant to erythromycin. Mutations in three different genes may confer resistance to erythromycin. Two of them are structural genes for proteins L4 and L22 of the large subunit. The third mutation (in eryC gene) seems to aff
The capablity of ribosomes of four types of streptomycin-resistant mutants (A1, A2, A40 and A60) for non-enzymatic (EF-G--GTP-independent) translocation was tested. It was found that an A40 type mutation (amino acid replacement in position 87 of the protein S12 polypeptide chain) leads to activation