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Ribosomes from erythromycin-resistant mutants of Escherichia coli Q13

✍ Scribed by Otaka, Eiko; Teraoka, Hiroshi; Tamaki, Mikio; Tanaka, Kentaro; Osawa, Syozo


Book ID
122786359
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
759 KB
Volume
48
Category
Article
ISSN
0022-2836

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Properties of ribosomes from erythromyci
✍ Pardo, Daniel ;Rosset, Roland πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 461 KB

We have studied the in vitro properties of ribosomes from several mutants resistant to erythromycin. Mutations in three different genes may confer resistance to erythromycin. Two of them are structural genes for proteins L4 and L22 of the large subunit. The third mutation (in eryC gene) seems to aff

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✍ Asatryan, L.S. ;Spirin, A.S. πŸ“‚ Article πŸ“… 1975 πŸ› Springer 🌐 English βš– 359 KB

The capablity of ribosomes of four types of streptomycin-resistant mutants (A1, A2, A40 and A60) for non-enzymatic (EF-G--GTP-independent) translocation was tested. It was found that an A40 type mutation (amino acid replacement in position 87 of the protein S12 polypeptide chain) leads to activation