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Rhodium-Catalyzed Hydroformylation of Unsaturated Esters.

✍ Scribed by Matthew L. Clarke


Publisher
John Wiley and Sons
Year
2004
Weight
172 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract Asymmetric hydroformylation of crotononitrile (**1**) and ally cyanide (**2**) was probed with the view to develop a synthesis for (__R__)‐4‐amino‐2‐methyl‐butan‐1‐ol. Hydroformylation of **1** under a variety of conditions mainly led to hydrogenated product. Hydroformylation of **2** w