𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Rhodium-Catalyzed Asymmetric Aqueous Pauson–Khand-Type Reaction

✍ Scribed by Fuk Yee Kwong; Yue Ming Li; Wai Har Lam; Liqin Qiu; Hang Wai Lee; Chi Hung Yeung; Kin Shing Chan; Albert S. C. Chan

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
295 KB
Volume
11
Category
Article
ISSN
0947-6539

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

An interesting rhodium‐catalyzed asymmetric aqueous Pauson–Khand‐type reaction was developed. A chiral atropisomeric dipyridyldiphosphane ligand was found to be highly effective in this system. This operationally simple protocol allows both catalyst and reactants to be handled under air without precautions. Various enynes were transformed to the corresponding bicyclic cyclopentenones in good yield and enantiomeric excess (up to 95 % ee). A study of the electronic effects of the enyne substrates revealed a correlation between the electronic properties of the substrates and the ee value obtained in the product of the Pauson–Khand‐type reaction. A linear free‐energy relationship was observed from a Hammett study.

📜 SIMILAR VOLUMES

Rhodium-Catalyzed Asymmetric Aqueous Pau
Rhodium-Catalyzed Asymmetric Aqueous Pauson—Khand-Type Reaction.
✍ Fuk Yee Kwong; Yue Ming Li; Wai Har Lam; Liqin Qiu; Hang Wai Lee; Chi Hung Yeung 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 27 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.