Rhodium (1) catalysed regiospecific cyclisation of 1,6-enynes to methylenecyclohex-2-enes
β Scribed by Ronald Grigg; Paul Stevenson; Tanachat Worakun
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 543 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
Various terminal alkynes in the presence of 5 mol% of RhCl(PPh 3 ) 3 were homo-coupled to the conjugated enynes. 1,6-Enynes in the presence of 5 mol% RhCl(PPh 3 ) 3 and 10 mol% Ag(I) salts underwent [2+2+2]-cyclization among two triple bonds and one pendant double bond in good to excellent yields.
Thc palladium-catal)sed 'mctallo-cnc' cyclisation, cyclisatimVcarbon~lation. -vinylstannane coupling, and Pd(lll-catalyscd chloropalladation/carboc?clisation of l,l-diacctox?-2,7-dienc and l.l-diacetoxy-2-cn-7-Snc derivatives are described The c3clic enolacetate products could rcadil 5 be comcrted i