Rhodium catalyzed [2+2+2] cyclizations of 1,6-enynes

✍ Scribed by Chang Ho Oh; Hye Rhyan Sung; Seung Hyun Jung; Young Mook Lim

• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 80 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)01065-6

✦ Synopsis

Various terminal alkynes in the presence of 5 mol% of RhCl(PPh 3 ) 3 were homo-coupled to the conjugated enynes. 1,6-Enynes in the presence of 5 mol% RhCl(PPh 3 ) 3 and 10 mol% Ag(I) salts underwent [2+2+2]-cyclization among two triple bonds and one pendant double bond in good to excellent yields.