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RhoA and RhoC differentially modulate estrogen receptor α recruitment, transcriptional activities, and expression in breast cancer cells (MCF-7)

✍ Scribed by Malissein, Emilie; Meunier, Elise; Lajoie-Mazenc, Isabelle; Médale-Giamarchi, Claire; Dalenc, Florence; Doisneau-Sixou, Sophie F.

Book ID
121604256
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
541 KB
Volume
139
Category
Article
ISSN
1432-1335

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## Abstract Estrogens play a key role in the development and evolution of breast cancer tumors. Estrogen receptor alpha (ERα) mediates many of the biological activities of estrogens, and its expression is associated with low invasiveness and good prognosis. Recent epidemiological reports suggest th