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Decrease of estrogen receptor expression and associated ERE-dependent transcription in MCF-7 breast cancer cells after oligomycin treatment

✍ Scribed by Hye-Sook Seo; Fabrice Journé; Denis Larsimont; Christos Sotiriou; Guy Leclercq

Book ID
117213577
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
479 KB
Volume
68
Category
Article
ISSN
0039-128X

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## Abstract Estrogens play a key role in the development and evolution of breast cancer tumors. Estrogen receptor alpha (ERα) mediates many of the biological activities of estrogens, and its expression is associated with low invasiveness and good prognosis. Recent epidemiological reports suggest th